| 28/09-21 |
UEFA Champions League
Group play - Leg 2 |
Real Madrid C.F. |
FC Sheriff Tiraspol |
| 03/10-21 |
Spanish Liga BBVA
La Liga - Matchday 8 |
R.C.D. Espanyol |
Real Madrid C.F. |
| 17/10-21 |
Spanish Liga BBVA
La Liga - Matchday 9 |
Real Madrid C.F. |
Athletic Bilbao |
| 19/10-21 |
UEFA Champions League
Group play - Leg 3 |
FC Shakhtar Donetsk |
Real Madrid C.F. |
| 24/10-21 |
Spanish Liga BBVA
La Liga - Matchday 10 |
F.C. Barcelona |
Real Madrid C.F. |
| 27/10-21 |
Spanish Liga BBVA
La Liga - Matchday 11 |
Real Madrid C.F. |
Osasuna |
| 31/10-21 |
Spanish Liga BBVA
La Liga - Matchday 12 |
Elche C.F. |
Real Madrid C.F. |
| 03/11-21 |
UEFA Champions League
Group play - Leg 4 |
Real Madrid C.F. |
FC Shakhtar Donetsk |
| 07/11-21 |
Spanish Liga BBVA
La Liga - Matchday 13 |
Real Madrid C.F. |
Rayo Vallecano |
| 21/11-21 |
Spanish Liga BBVA
La Liga - Matchday 14 |
Granada CF |
Real Madrid C.F. |
| 24/11-21 |
UEFA Champions League
Group play - Leg 5 |
FC Sheriff Tiraspol |
Real Madrid C.F. |
| 28/11-21 |
Spanish Liga BBVA
La Liga - Matchday 15 |
Real Madrid C.F. |
Sevilla F.C. |
| 05/12-21 |
Spanish Liga BBVA
La Liga - Matchday 16 |
Real Sociedad |
Real Madrid C.F. |
| 07/12-21 |
UEFA Champions League
Group play - Leg 6 |
Real Madrid C.F. |
Inter Milan |
| 12/12-21 |
Spanish Liga BBVA
La Liga - Matchday 17 |
Real Madrid C.F. |
Atletico Madrid |
| 19/12-21 |
Spanish Liga BBVA
La Liga - Matchday 18 |
Real Madrid C.F. |
Cadiz CF |
| 02/01-22 |
Spanish Liga BBVA
La Liga - Matchday 19 |
Getafe C.F. |
Real Madrid C.F. |
| 09/01-22 |
Spanish Liga BBVA
La Liga - Matchday 20 |
Real Madrid C.F. |
Valencia C.F. |
| 13/01-22 |
Spanish Super Cup
Semifinal |
F.C. Barcelona |
Real Madrid C.F. |
| 19/01-22 |
Spanish Liga BBVA
La Liga - Matchday 21 |
Athletic Bilbao |
Real Madrid C.F. |
| 23/01-22 |
Spanish Liga BBVA
La Liga - Matchday 22 |
Real Madrid C.F. |
Elche C.F. |
| 06/02-22 |
Spanish Liga BBVA
La Liga - Matchday 23 |
Real Madrid C.F. |
Granada CF |
| 13/02-22 |
Spanish Liga BBVA
La Liga - Matchday 24 |
Villarreal C.F. |
Real Madrid C.F. |
| 20/02-22 |
Spanish Liga BBVA
La Liga - Matchday 25 |
Real Madrid C.F. |
Dep. Alavés |
| 27/02-22 |
Spanish Liga BBVA
La Liga - Matchday 26 |
Rayo Vallecano |
Real Madrid C.F. |
| 06/03-22 |
Spanish Liga BBVA
La Liga - Matchday 27 |
Real Madrid C.F. |
Real Sociedad |
| 13/03-22 |
Spanish Liga BBVA
La Liga - Matchday 28 |
R.C.D. Mallorca |
Real Madrid C.F. |
| 20/03-22 |
Spanish Liga BBVA
La Liga - Matchday 29 |
Real Madrid C.F. |
F.C. Barcelona |
| 03/04-22 |
Spanish Liga BBVA
La Liga - Matchday 30 |
Celta de Vigo |
Real Madrid C.F. |
| 10/04-22 |
Spanish Liga BBVA
La Liga - Matchday 31 |
Real Madrid C.F. |
Getafe C.F. |
| 17/04-22 |
Spanish Liga BBVA
La Liga - Matchday 32 |
Sevilla F.C. |
Real Madrid C.F. |
| 20/04-22 |
Spanish Liga BBVA
La Liga - Matchday 33 |
Osasuna |
Real Madrid C.F. |
| 01/05-22 |
Spanish Liga BBVA
La Liga - Matchday 34 |
Real Madrid C.F. |
R.C.D. Espanyol |
| 08/05-22 |
Spanish Liga BBVA
La Liga - Matchday 35 |
Atletico Madrid |
Real Madrid C.F. |
| 11/05-22 |
Spanish Liga BBVA
La Liga - Matchday 36 |
Real Madrid C.F. |
Levante Unión Deportiva |
| 15/05-22 |
Spanish Liga BBVA
La Liga - Matchday 37 |
Cadiz CF |
Real Madrid C.F. |
| 22/05-22 |
Spanish Liga BBVA
La Liga - Matchday 38 |
Real Madrid C.F. |
Real Betis |