Louis van Gaal has been tracking the centre back all summer and could be close to getting his man.
Ramos is desperate to leave but Madrid had resisted selling him at all costs.
But now, Spanish journalist Pablo Garcia Cuervo has revealed that Real president Florentino Perez has finally decided to cash-in on the unsettled defender.
He told Radio Marca: "Sergio has made his mind up."
"Florentino also wants Sergio to leave, but Real Madrid want it to seem like Sergio is the one who wants to leave because he isn’t very ‘madridista’.