Raphael Varane sustained an injury that leaves Real Madrid with just one centre-back available to face Sevilla.
Raphael Varane will miss Real Madrid's LaLiga clash with Sevilla on Saturday through injury, adding to Zinedine Zidane's defensive concerns.
Centre-back Varane walked off the pitch in the 38th minute of Madrid's 3-2 Champions League victory over Borussia Dortmund on Wednesday with what appeared to be a muscular issue.
The loss of the 24-year-old for the visit of Eduardo Berizzo's side, level with Madrid on 28 points in LaLiga, is a bitter blow for Zidane, who will be without suspended trio Sergio Ramos, Dani Carvajal and Casemiro, while Cesar Vallejo is injured.
"He hurt himself and we will see. Tomorrow [Thursday] they will do a scan. The player is optimistic but he will not be available on Saturday, that's for sure," said Zidane, before admitting midfielder Marcos Llorente may have to slot into the back four.